Smoking, Alcohol and (O)esophageal Cancer
Data from a case-control study of (o)esophageal cancer in
Ille-et-Vilaine, France.
Usage
esoph
Format
A data frame with records for 88 age/alcohol/tobacco combinations.
[,1] | "agegp" | Age group | 1 25--34 years |
| | | 2 35--44 |
| | | 3 45--54 |
| | | 4 55--64 |
| | | 5 65--74 |
| | | 6 75+ |
[,2] | "alcgp" | Alcohol consumption | 1 0--39 gm/day |
| | | 2 40--79 |
| | | 3 80--119 |
| | | 4 120+ |
[,3] | "tobgp" | Tobacco consumption | 1 0-- 9 gm/day |
| | | 2 10--19 |
| | | 3 20--29 |
| | | 4 30+ |
[,4] | "ncases" | Number of cases | |
[,5] | "ncontrols" | Number of controls |
|
Author(s)
Thomas Lumley
Source
Breslow, N. E. and Day, N. E. (1980)
Statistical Methods in Cancer Research. Volume 1: The Analysis of
Case-Control Studies. IARC Lyon / Oxford University Press.
Examples
require(stats)
require(graphics) # for mosaicplot
summary(esoph)
## effects of alcohol, tobacco and interaction, age-adjusted
model1 <- glm(cbind(ncases, ncontrols) ~ agegp + tobgp * alcgp,
data = esoph, family = binomial())
anova(model1)
## Try a linear effect of alcohol and tobacco
model2 <- glm(cbind(ncases, ncontrols) ~ agegp + unclass(tobgp)
+ unclass(alcgp),
data = esoph, family = binomial())
summary(model2)
## Re-arrange data for a mosaic plot
ttt <- table(esoph$agegp, esoph$alcgp, esoph$tobgp)
o <- with(esoph, order(tobgp, alcgp, agegp))
ttt[ttt == 1] <- esoph$ncases[o]
tt1 <- table(esoph$agegp, esoph$alcgp, esoph$tobgp)
tt1[tt1 == 1] <- esoph$ncontrols[o]
tt <- array(c(ttt, tt1), c(dim(ttt),2),
c(dimnames(ttt), list(c("Cancer", "control"))))
mosaicplot(tt, main = "esoph data set", color = TRUE)
|